面议  |   Cambridge(UK)

2017-03-26 发布 / 截止至 2017-05-19 分享至

欧洲 生物 生物化学 分子生物学 企业


Base4 introduction:

Base4 is a company based in Cambridge, UK, developing a completely new method of single-molecule DNA sequencing. The technique allows for both short and long read lengths, direct readout of methylation, simple instrumentation, low reagent volumes, and unparalleled control over the input sample.

We have developed a novel chemistry which releases nucleotides from DNA and generates a bright fluorescent signal from each individual nucleotide, allowing us to detect them with impressive accuracy.

Job description:

We are seeking creative, ambitious biochemists to join our development team to work on the optimisation of this new sequencing chemistry and development of new chemistries as well as on extending our capabilities beyond the detection of the four common DNA bases.


You will ideally be qualified to PhD level with a strong background in enzymology and molecular biology. The role requires a mastery of standard molecular biology techniques, plus an ability and interest in applying them in unusual or novel ways.

The ideal candidate would have experience in at least some of the following areas:

• Development and optimisation of DNA preparation techniques
• Enzymatic modification of DNA
• Oligonucleotide design
• Chemical/oligonucleotide purification and analysis
• Library preparation for DNA sequencing

To be a successful a candidate you must be eligible to work in the UK and be able to thrive in a team of competent, intellectually competitive people. Creative thinking coupled with intellectual curiosity and a desire to tackle substantial problems is essential.


To apply for one of these opportunities please email your CV and covering letter to

Please visit for further information on the company.

Strictly no agencies as only direct applicants will be considered for these roles